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4-Methylumbelliferone Inhibits Cancer Stem Cell Activation and Overcomes Chemoresistance in Ovarian Cancer

We have recently shown that the extracellular matrix molecule hyaluronan (HA) plays a role in the development of ovarian cancer chemoresistance. This present study determined if HA production is increased in chemotherapy-resistant ovarian cancers and if the HA inhibitor 4-methylubelliferone (4-MU) c...

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Detalles Bibliográficos
Autores principales: Lokman, Noor A., Price, Zoe K., Hawkins, Emily K., Macpherson, Anne M., Oehler, Martin K., Ricciardelli, Carmela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721459/
https://www.ncbi.nlm.nih.gov/pubmed/31443261
http://dx.doi.org/10.3390/cancers11081187