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HMGA1 Modulates Gene Transcription Sustaining a Tumor Signalling Pathway Acting on the Epigenetic Status of Triple-Negative Breast Cancer Cells

Chromatin accessibility plays a critical factor in regulating gene expression in cancer cells. Several factors, including the High Mobility Group A (HMGA) family members, are known to participate directly in chromatin relaxation and transcriptional activation. The HMGA1 oncogene encodes an architect...

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Detalles Bibliográficos
Autores principales: Penzo, Carlotta, Arnoldo, Laura, Pegoraro, Silvia, Petrosino, Sara, Ros, Gloria, Zanin, Rossella, Wiśniewski, Jacek R., Manfioletti, Guidalberto, Sgarra, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721465/
https://www.ncbi.nlm.nih.gov/pubmed/31382504
http://dx.doi.org/10.3390/cancers11081105