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p21 in Cancer Research

p21 functions as a cell cycle inhibitor and anti-proliferative effector in normal cells, and is dysregulated in some cancers. Earlier observations on p21 knockout models emphasized the role of this protein in cell cycle arrest under the p53 transcription factor activity. Although tumor-suppressor fu...

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Detalles Bibliográficos
Autores principales: Shamloo, Bahar, Usluer, Sinem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721478/
https://www.ncbi.nlm.nih.gov/pubmed/31416295
http://dx.doi.org/10.3390/cancers11081178