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DNA-Methylation-Caused Downregulation of miR-30 Contributes to the High Expression of XPO1 and the Aggressive Growth of Tumors in Pancreatic Ductal Adenocarcinoma

Pancreatic ductal adenocarcinoma is one of the most aggressive cancers, with high mortality in the United States. One of the important signal transduction proteins involved in the regulation of pancreatic cancer’s aggressive progression is the nuclear export protein (XPO1). High expression of XPO1 h...

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Detalles Bibliográficos
Autores principales: Azmi, Asfar S., Li, Yiwei, Aboukameel, Amro, Muqbil, Irfana, Philip, Philip A., Mohammad, Ramzi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721494/
https://www.ncbi.nlm.nih.gov/pubmed/31382411
http://dx.doi.org/10.3390/cancers11081101