The Hedgehog Signaling Pathway: A Viable Target in Breast Cancer?

The hedgehog (Hh) pathway plays a key role in embryonic development and stem cell programs. Deregulation of the Hh pathway is a key driver of basal cell carcinoma, and therapeutic targeting led to approval of Hh inhibitor, vismodegib, in the management of this cancer. The Hh pathway is implicated in...

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Detalles Bibliográficos
Autores principales: Bhateja, Priyanka, Cherian, Mathew, Majumder, Sarmila, Ramaswamy, Bhuvaneswari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721501/
https://www.ncbi.nlm.nih.gov/pubmed/31394751
http://dx.doi.org/10.3390/cancers11081126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721501/
https://www.ncbi.nlm.nih.gov/pubmed/31394751
http://dx.doi.org/10.3390/cancers11081126

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