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The Hedgehog Signaling Pathway: A Viable Target in Breast Cancer?
The hedgehog (Hh) pathway plays a key role in embryonic development and stem cell programs. Deregulation of the Hh pathway is a key driver of basal cell carcinoma, and therapeutic targeting led to approval of Hh inhibitor, vismodegib, in the management of this cancer. The Hh pathway is implicated in...
Autores principales: | Bhateja, Priyanka, Cherian, Mathew, Majumder, Sarmila, Ramaswamy, Bhuvaneswari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721501/ https://www.ncbi.nlm.nih.gov/pubmed/31394751 http://dx.doi.org/10.3390/cancers11081126 |
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