Structural Consequences of Copper Binding to the Prion Protein

Prion, or PrP(Sc), is the pathological isoform of the cellular prion protein (PrP(C)) and it is the etiological agent of transmissible spongiform encephalopathies (TSE) affecting humans and animal species. The most relevant function of PrP(C) is its ability to bind copper ions through its flexible N...

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Detalles Bibliográficos
Autores principales: Salzano, Giulia, Giachin, Gabriele, Legname, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721516/
https://www.ncbi.nlm.nih.gov/pubmed/31349611
http://dx.doi.org/10.3390/cells8080770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721516/
https://www.ncbi.nlm.nih.gov/pubmed/31349611
http://dx.doi.org/10.3390/cells8080770

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