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Impact of Heat Shock Protein 90 Inhibition on the Proteomic Profile of Lung Adenocarcinoma as Measured by Two-Dimensional Electrophoresis Coupled with Mass Spectrometry

Heat shock protein 90 (HSP90) is an important chaperone in lung adenocarcinoma, with relevant protein drivers such as EGFR (epidermal growth factor receptor) and EML4-ALK (echinoderm microtubule-associated protein-like protein4 fused to anaplastic lymphoma kinase) depending on it for their correct f...

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Detalles Bibliográficos
Autores principales: Marrugal, Ángela, Ferrer, Irene, Pastor, Maria Dolores, Ojeda, Laura, Quintanal-Villalonga, Álvaro, Carnero, Amancio, Molina-Pinelo, Sonia, Paz-Ares, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721529/
https://www.ncbi.nlm.nih.gov/pubmed/31370342
http://dx.doi.org/10.3390/cells8080806