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Epigenome Mapping Identifies Tumor-Specific Gene Expression in Primary Rectal Cancer

Epigenetic alterations play a central role in cancer development and progression. The acetylation of histone 3 at lysine 27 (H3K27ac) specifically marks active genes. While chromatin immunoprecipitation (ChIP) followed by next-generation sequencing (ChIP-seq) analyses are commonly performed in cell...

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Detalles Bibliográficos
Autores principales: Flebbe, Hannah, Hamdan, Feda H., Kari, Vijayalakshmi, Kitz, Julia, Gaedcke, Jochen, Ghadimi, B. Michael, Johnsen, Steven A., Grade, Marian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721540/
https://www.ncbi.nlm.nih.gov/pubmed/31404997
http://dx.doi.org/10.3390/cancers11081142