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Single-Cell Analysis of Multiple Steps of Dynamic NF-κB Regulation in Interleukin-1α-Triggered Tumor Cells Using Proximity Ligation Assays

The frequently occurring heterogeneity of cancer cells and their functional interaction with immune cells in the tumor microenvironment raises the need to study signaling pathways at the single cell level with high precision, sensitivity, and spatial resolution. As aberrant NF-κB activity has been i...

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Detalles Bibliográficos
Autores principales: Mayr-Buro, Christin, Schlereth, Eva, Beuerlein, Knut, Tenekeci, Ulas, Meier-Soelch, Johanna, Schmitz, M. Lienhard, Kracht, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721548/
https://www.ncbi.nlm.nih.gov/pubmed/31426445
http://dx.doi.org/10.3390/cancers11081199