Role and Therapeutic Targeting of the PI3K/Akt/mTOR Signaling Pathway in Skin Cancer: A Review of Current Status and Future Trends on Natural and Synthetic Agents Therapy

The mammalian or mechanistic target of rapamycin (mTOR) and associated phosphatidyl-inositiol 3-kinase (PI3K)/protein kinase B (Akt) pathways regulate cell growth, differentiation, migration, and survival, as well as angiogenesis and metabolism. Dysregulation of these pathways is frequently associat...

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Detalles Bibliográficos
Autores principales: Chamcheu, Jean Christopher, Roy, Tithi, Uddin, Mohammad Burhan, Banang-Mbeumi, Sergette, Chamcheu, Roxane-Cherille N., Walker, Anthony L., Liu, Yong-Yu, Huang, Shile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721560/
https://www.ncbi.nlm.nih.gov/pubmed/31370278
http://dx.doi.org/10.3390/cells8080803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721560/
https://www.ncbi.nlm.nih.gov/pubmed/31370278
http://dx.doi.org/10.3390/cells8080803

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