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Coagulation Factor Xa Promotes Solid Tumor Growth, Experimental Metastasis and Endothelial Cell Activation

Hypercoagulable state is linked to cancer progression; however, the precise role of the coagulation cascade is poorly described. Herein, we examined the contribution of a hypercoagulative state through the administration of intravenous Coagulation Factor Xa (FXa), on the growth of solid human tumors...

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Detalles Bibliográficos
Autores principales: Arce, Maximiliano, Pinto, Mauricio P., Galleguillos, Macarena, Muñoz, Catalina, Lange, Soledad, Ramirez, Carolina, Erices, Rafaela, Gonzalez, Pamela, Velasquez, Ethel, Tempio, Fabián, Lopez, Mercedes N., Salazar-Onfray, Flavio, Cautivo, Kelly, Kalergis, Alexis M., Cruz, Sebastián, Lladser, Álvaro, Lobos-González, Lorena, Valenzuela, Guillermo, Olivares, Nixa, Sáez, Claudia, Koning, Tania, Sánchez, Fabiola A., Fuenzalida, Patricia, Godoy, Alejandro, Contreras Orellana, Pamela, Leyton, Lisette, Lugano, Roberta, Dimberg, Anna, Quest, Andrew F.G., Owen, Gareth I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721564/
https://www.ncbi.nlm.nih.gov/pubmed/31382462
http://dx.doi.org/10.3390/cancers11081103