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A Role for the WNT Co-Receptor LRP6 in Pathogenesis and Therapy of Epithelial Cancers

The WNT/β-catenin signaling pathway controls stem and progenitor cell proliferation, survival and differentiation in epithelial tissues. Aberrant stimulation of this pathway is therefore frequently observed in cancers from epithelial origin. For instance, colorectal and hepatic cancers display activ...

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Detalles Bibliográficos
Autores principales: Raisch, Jennifer, Côté-Biron, Anthony, Rivard, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721565/
https://www.ncbi.nlm.nih.gov/pubmed/31412666
http://dx.doi.org/10.3390/cancers11081162