The Importance of Gender-Related Anticancer Research on Mitochondrial Regulator Sodium Dichloroacetate in Preclinical Studies In Vivo

Sodium dichloroacetate (DCA) is an investigational medicinal product which has a potential anticancer preparation as a metabolic regulator in cancer cells’ mitochondria. Inhibition of pyruvate dehydrogenase kinases by DCA keeps the pyruvate dehydrogenase complex in the active form, resulting in decr...

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Detalles Bibliográficos
Autores principales: Stakišaitis, Donatas, Juknevičienė, Milda, Damanskienė, Eligija, Valančiūtė, Angelija, Balnytė, Ingrida, Alonso, Marta Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721567/
https://www.ncbi.nlm.nih.gov/pubmed/31434295
http://dx.doi.org/10.3390/cancers11081210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721567/
https://www.ncbi.nlm.nih.gov/pubmed/31434295
http://dx.doi.org/10.3390/cancers11081210

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