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LAG3: The Biological Processes That Motivate Targeting This Immune Checkpoint Molecule in Human Cancer

The programmed cell death 1 (PD-1) pathway is an important regulator of immune responses in peripheral tissues, including abnormal situations such as the tumor microenvironment. This pathway is currently the principal target for immunotherapeutic compounds designed to block immune checkpoint pathway...

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Detalles Bibliográficos
Autores principales: Solinas, Cinzia, Migliori, Edoardo, De Silva, Pushpamali, Willard-Gallo, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721578/
https://www.ncbi.nlm.nih.gov/pubmed/31434339
http://dx.doi.org/10.3390/cancers11081213