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LAG3: The Biological Processes That Motivate Targeting This Immune Checkpoint Molecule in Human Cancer
The programmed cell death 1 (PD-1) pathway is an important regulator of immune responses in peripheral tissues, including abnormal situations such as the tumor microenvironment. This pathway is currently the principal target for immunotherapeutic compounds designed to block immune checkpoint pathway...
Autores principales: | Solinas, Cinzia, Migliori, Edoardo, De Silva, Pushpamali, Willard-Gallo, Karen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721578/ https://www.ncbi.nlm.nih.gov/pubmed/31434339 http://dx.doi.org/10.3390/cancers11081213 |
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