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Targeting Heat Shock Protein 27 in Cancer: A Druggable Target for Cancer Treatment?

Heat shock protein 27 (HSP27), induced by heat shock, environmental, and pathophysiological stressors, is a multi-functional protein that acts as a protein chaperone and an antioxidant. HSP27 plays a significant role in the inhibition of apoptosis and actin cytoskeletal remodeling. HSP27 is upregula...

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Detalles Bibliográficos
Autores principales: Choi, Seul-Ki, Kam, Heejin, Kim, Kye-Young, Park, Suk In, Lee, Yun-Sil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721579/
https://www.ncbi.nlm.nih.gov/pubmed/31426426
http://dx.doi.org/10.3390/cancers11081195