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Immune-Deficient Pfp/Rag2(−/−) Mice Featured Higher Adipose Tissue Mass and Liver Lipid Accumulation with Growing Age than Wildtype C57BL/6N Mice

Aging is a risk factor for adipose tissue dysfunction, which is associated with inflammatory innate immune mechanisms. Since the adipose tissue/liver axis contributes to hepatosteatosis, we sought to determine age-related adipose tissue dysfunction in the context of the activation of the innate immu...

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Detalles Bibliográficos
Autores principales: Winkler, Sandra, Hempel, Madlen, Hsu, Mei-Ju, Gericke, Martin, Kühne, Hagen, Brückner, Sandra, Erler, Silvio, Burkhardt, Ralph, Christ, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721582/
https://www.ncbi.nlm.nih.gov/pubmed/31349725
http://dx.doi.org/10.3390/cells8080775