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TIMP-1-Mediated Chemoresistance via Induction of IL-6 in NSCLC

Elevated tissue inhibitor of metalloproteinase-1 (TIMP-1) is a negative prognosticator in non-small cell lung carcinoma NSCLC patients. This study sought to identify mechanisms whereby TIMP-1 impacts anticancer therapy. Using NSCLC cells and their TIMP-1 knockdown clones, we examined the chemoresist...

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Detalles Bibliográficos
Autores principales: Xiao, Wei, Wang, Lan, Howard, John, Kolhe, Ravindra, Rojiani, Amyn M., Rojiani, Mumtaz V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721590/
https://www.ncbi.nlm.nih.gov/pubmed/31443242
http://dx.doi.org/10.3390/cancers11081184