Molecular Mechanisms Associated with ROR1-Mediated Drug Resistance: Crosstalk with Hippo-YAP/TAZ and BMI-1 Pathways

Signaling via the Wnt-related receptor tyrosine kinase-like orphan receptor 1 (ROR1) triggers tumorigenic features associated with cancer stem cells (CSCs) and epithelial–mesenchymal transition (EMT), while aberrant expression of ROR1 is strongly linked to advanced disease progression and chemoresis...

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Detalles Bibliográficos
Autores principales: Karvonen, Hanna, Barker, Harlan, Kaleva, Laura, Niininen, Wilhelmiina, Ungureanu, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721603/
https://www.ncbi.nlm.nih.gov/pubmed/31382410
http://dx.doi.org/10.3390/cells8080812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721603/
https://www.ncbi.nlm.nih.gov/pubmed/31382410
http://dx.doi.org/10.3390/cells8080812

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