ERCC1 Is a Predictor of Anthracycline Resistance and Taxane Sensitivity in Early Stage or Locally Advanced Breast Cancers

Genomic instability could be a beneficial predictor for anthracycline or taxane chemotherapy. We interrogated 188 DNA repair genes in the METABRIC cohort (n = 1980) to identify genes that influence overall survival (OS). We then evaluated the clinicopathological significance of ERCC1 in early stage...

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Detalles Bibliográficos
Autores principales: Abdel-Fatah, Tarek M. A., Ali, Reem, Sadiq, Maaz, Moseley, Paul M., Mesquita, Katia A., Ball, Graham, Green, Andrew R., Rakha, Emad A., Chan, Stephen Y. T., Madhusudan, Srinivasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721618/
https://www.ncbi.nlm.nih.gov/pubmed/31405143
http://dx.doi.org/10.3390/cancers11081149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721618/
https://www.ncbi.nlm.nih.gov/pubmed/31405143
http://dx.doi.org/10.3390/cancers11081149

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