Whole Transcriptome Analysis Identifies TNS4 as a Key Effector of Cetuximab and a Regulator of the Oncogenic Activity of KRAS Mutant Colorectal Cancer Cell Lines

The targeting of activated epidermal growth factor receptor (EGFR) with therapeutic anti-EGFR monoclonal antibodies (mAbs) such as cetuximab and panitumumab has been used as an effective strategy in the treatment of colorectal cancer (CRC). However, its clinical efficacy occurs only in a limited num...

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Detalles Bibliográficos
Autores principales: Kim, Sujin, Kim, Nayoung, Kang, Keunsoo, Kim, Wonkyung, Won, Jonghwa, Cho, Jeonghee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721647/
https://www.ncbi.nlm.nih.gov/pubmed/31409052
http://dx.doi.org/10.3390/cells8080878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721647/
https://www.ncbi.nlm.nih.gov/pubmed/31409052
http://dx.doi.org/10.3390/cells8080878

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