Epigenetic Changes as a Target in Aging Haematopoietic Stem Cells and Age-Related Malignancies

Aging is associated with multiple molecular and functional changes in haematopoietic cells. Most notably, the self-renewal and differentiation potential of hematopoietic stem cells (HSCs) are compromised, resulting in myeloid skewing, reduced output of red blood cells and decreased generation of imm...

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Detalles Bibliográficos
Autores principales: Buisman, Sonja C., de Haan, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721661/
https://www.ncbi.nlm.nih.gov/pubmed/31405121
http://dx.doi.org/10.3390/cells8080868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721661/
https://www.ncbi.nlm.nih.gov/pubmed/31405121
http://dx.doi.org/10.3390/cells8080868

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