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Deep Sequencing Reveals Central Nervous System Compartmentalization in Multiple Transmitted/Founder Virus Acute HIV-1 Infection

HIV-1 disseminates to a broad range of tissue compartments during acute HIV-1 infection (AHI). The central nervous system (CNS) can serve as an early and persistent site of viral replication, which poses a potential challenge for HIV-1 remission strategies that target the HIV reservoir. CNS compartm...

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Detalles Bibliográficos
Autores principales: Tovanabutra, Sodsai, Sirijatuphat, Rujipas, Pham, Phuc T., Bonar, Lydia, Harbolick, Elizabeth A., Bose, Meera, Song, Hongshuo, Chang, David, Oropeza, Celina, O’Sullivan, Anne Marie, Balinang, Joyce, Kroon, Eugene, Colby, Donn J., Sacdalan, Carlo, Hellmuth, Joanna, Chan, Phillip, Prueksakaew, Peeriya, Pinyakorn, Suteeraporn, Jagodzinski, Linda L., Sutthichom, Duanghathai, Pattamaswin, Suwanna, de Souza, Mark, Gramzinski, Robert A., Kim, Jerome H., Michael, Nelson L., Robb, Merlin L., Phanuphak, Nittaya, Ananworanich, Jintanat, Valcour, Victor, Kijak, Gustavo H., Sanders-Buell, Eric, Spudich, Serena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721674/
https://www.ncbi.nlm.nih.gov/pubmed/31443253
http://dx.doi.org/10.3390/cells8080902