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N-Acetylcysteine Serves as Substrate of 3-Mercaptopyruvate Sulfurtransferase and Stimulates Sulfide Metabolism in Colon Cancer Cells

Hydrogen sulfide (H(2)S) is an endogenously produced signaling molecule. The enzymes 3-mercaptopyruvate sulfurtransferase (MST), partly localized in mitochondria, and the inner mitochondrial membrane-associated sulfide:quinone oxidoreductase (SQR), besides being respectively involved in the synthesi...

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Detalles Bibliográficos
Autores principales: Zuhra, Karim, Tomé, Catarina S., Masi, Letizia, Giardina, Giorgio, Paulini, Giulia, Malagrinò, Francesca, Forte, Elena, Vicente, João B., Giuffrè, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721681/
https://www.ncbi.nlm.nih.gov/pubmed/31382676
http://dx.doi.org/10.3390/cells8080828