Extracellular Juxtamembrane Motif Critical for TrkB Preformed Dimer and Activation

Receptor tyrosine kinases are believed to be activated through ligand-induced dimerization. We now demonstrate that in cultured neurons, a substantial amount of endogenous TrkB, the receptor for brain-derived neurotrophic factor (BDNF), exists as an inactive preformed dimer, and the application of B...

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Detalles Bibliográficos
Autores principales: Shen, Jianying, Sun, Dang, Shao, Jingyu, Chen, Yanbo, Pang, Keliang, Guo, Wei, Lu, Bai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721692/
https://www.ncbi.nlm.nih.gov/pubmed/31430955
http://dx.doi.org/10.3390/cells8080932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721692/
https://www.ncbi.nlm.nih.gov/pubmed/31430955
http://dx.doi.org/10.3390/cells8080932

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