Calcitriol Attenuates Doxorubicin-Induced Cardiac Dysfunction and Inhibits Endothelial-to-Mesenchymal Transition in Mice

Doxorubicin (Dox) is an effective anti-neoplasm drug, but its cardiac toxicity limits its clinical use. Endothelial-to-mesenchymal transition (EndMT) has been found to be involved in the process of heart failure. It is unclear whether EndMT contributes to Dox-induced cardiomyopathy (DoIC). Calcitrio...

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Detalles Bibliográficos
Autores principales: Tsai, Tzu-Hsien, Lin, Cheng-Jei, Hang, Chi-Ling, Chen, Wei-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721693/
https://www.ncbi.nlm.nih.gov/pubmed/31405028
http://dx.doi.org/10.3390/cells8080865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721693/
https://www.ncbi.nlm.nih.gov/pubmed/31405028
http://dx.doi.org/10.3390/cells8080865

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