Cargando…

Fatty Acid and Lipopolysaccharide Effect on Beta Cells Proteostasis and its Impact on Insulin Secretion

Metabolic overload by saturated fatty acids (SFA), which comprises β-cell function, and impaired glucose-stimulated insulin secretion are frequently observed in patients suffering from obesity and type 2 diabetes mellitus. The increase of intracellular Ca(2+) triggers insulin granule release, theref...

Descripción completa

Detalles Bibliográficos
Autores principales: Acosta-Montaño, Paloma, Rodríguez-Velázquez, Eustolia, Ibarra-López, Esmeralda, Frayde-Gómez, Héctor, Mas-Oliva, Jaime, Delgado-Coello, Blanca, Rivero, Ignacio A., Alatorre-Meda, Manuel, Aguilera, Jorge, Guevara-Olaya, Lizbeth, García-González, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721695/
https://www.ncbi.nlm.nih.gov/pubmed/31412623
http://dx.doi.org/10.3390/cells8080884