Modulation of Agrin and RhoA Pathways Ameliorates Movement Defects and Synapse Morphology in MYO9A-Depleted Zebrafish

Congenital myasthenic syndromes (CMS) are a group of rare, inherited disorders characterised by impaired function of the neuromuscular junction (NMJ). This is due to defects in one of the many proteins associated with the NMJ. In three patients with CMS, missense mutations in a gene encoding an unco...

Descripción completa

Detalles Bibliográficos
Autores principales: O’Connor, Emily, Cairns, George, Spendiff, Sally, Burns, David, Hettwer, Stefan, Mäder, Armin, Müller, Juliane, Horvath, Rita, Slater, Clarke, Roos, Andreas, Lochmüller, Hanns
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721702/
https://www.ncbi.nlm.nih.gov/pubmed/31394789
http://dx.doi.org/10.3390/cells8080848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721702/
https://www.ncbi.nlm.nih.gov/pubmed/31394789
http://dx.doi.org/10.3390/cells8080848

Ejemplares similares