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Modulation of Agrin and RhoA Pathways Ameliorates Movement Defects and Synapse Morphology in MYO9A-Depleted Zebrafish
Congenital myasthenic syndromes (CMS) are a group of rare, inherited disorders characterised by impaired function of the neuromuscular junction (NMJ). This is due to defects in one of the many proteins associated with the NMJ. In three patients with CMS, missense mutations in a gene encoding an unco...
Autores principales: | O’Connor, Emily, Cairns, George, Spendiff, Sally, Burns, David, Hettwer, Stefan, Mäder, Armin, Müller, Juliane, Horvath, Rita, Slater, Clarke, Roos, Andreas, Lochmüller, Hanns |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721702/ https://www.ncbi.nlm.nih.gov/pubmed/31394789 http://dx.doi.org/10.3390/cells8080848 |
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