Cargando…

The NAE Pathway: Autobahn to the Nucleus for Cell Surface Receptors

Various growth factors and full-length cell surface receptors such as EGFR are translocated from the cell surface to the nucleoplasm, baffling cell biologists to the mechanisms and functions of this process. Elevated levels of nuclear EGFR correlate with poor prognosis in various cancers. In recent...

Descripción completa

Detalles Bibliográficos
Autores principales: Shah, Poonam, Chaumet, Alexandre, Royle, Stephen J., Bard, Frederic A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721735/
https://www.ncbi.nlm.nih.gov/pubmed/31426451
http://dx.doi.org/10.3390/cells8080915