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Roles of JAK2 in Aging, Inflammation, Hematopoiesis and Malignant Transformation
Clonal alterations in hematopoietic cells occur during aging and are often associated with the establishment of a subclinical inflammatory environment. Several age-related conditions and diseases may be initiated or promoted by these alterations. JAK2 mutations are among the most frequently mutated...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721738/ https://www.ncbi.nlm.nih.gov/pubmed/31398915 http://dx.doi.org/10.3390/cells8080854 |