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HSPA8/HSC70 in Immune Disorders: A Molecular Rheostat that Adjusts Chaperone-Mediated Autophagy Substrates

HSPA8/HSC70 is a molecular chaperone involved in a wide variety of cellular processes. It plays a crucial role in protein quality control, ensuring the correct folding and re-folding of selected proteins, and controlling the elimination of abnormally-folded conformers and of proteins daily produced...

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Detalles Bibliográficos
Autores principales: Bonam, Srinivasa Reddy, Ruff, Marc, Muller, Sylviane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721745/
https://www.ncbi.nlm.nih.gov/pubmed/31394830
http://dx.doi.org/10.3390/cells8080849