Parkin-Dependent Mitophagy Is Required for the Inhibition of ATF4 on NLRP3 Inflammasome Activation in Cerebral Ischemia-Reperfusion Injury in Rats

Background: Nod-like receptor protein 3 (NLRP3) inflammasome is a crucial contributor in the inflammatory process during cerebral ischemia/reperfusion (I/R) injury. ATF4 plays a pivotal role in the pathogenesis of cerebral I/R injury, however, its function and underlying mechanism are not fully char...

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Detalles Bibliográficos
Autores principales: He, Qi, Li, Zhenyu, Meng, Changchang, Wu, Jingxian, Zhao, Yong, Zhao, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721752/
https://www.ncbi.nlm.nih.gov/pubmed/31416289
http://dx.doi.org/10.3390/cells8080897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721752/
https://www.ncbi.nlm.nih.gov/pubmed/31416289
http://dx.doi.org/10.3390/cells8080897

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