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The Combination of IFN β and TNF Induces an Antiviral and Immunoregulatory Program via Non-Canonical Pathways Involving STAT2 and IRF9

Interferon (IFN) β and Tumor Necrosis Factor (TNF) are key players in immunity against viruses. Compelling evidence has shown that the antiviral and inflammatory transcriptional response induced by IFNβ is reprogrammed by crosstalk with TNF. IFNβ mainly induces interferon-stimulated genes by the Jan...

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Detalles Bibliográficos
Autores principales: Mariani, Mélissa K., Dasmeh, Pouria, Fortin, Audray, Caron, Elise, Kalamujic, Mario, Harrison, Alexander N., Hotea, Diana I., Kasumba, Dacquin M., Cervantes-Ortiz, Sandra L., Mukawera, Espérance, Serohijos, Adrian W. R., Grandvaux, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721756/
https://www.ncbi.nlm.nih.gov/pubmed/31426476
http://dx.doi.org/10.3390/cells8080919