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The Combination of IFN β and TNF Induces an Antiviral and Immunoregulatory Program via Non-Canonical Pathways Involving STAT2 and IRF9
Interferon (IFN) β and Tumor Necrosis Factor (TNF) are key players in immunity against viruses. Compelling evidence has shown that the antiviral and inflammatory transcriptional response induced by IFNβ is reprogrammed by crosstalk with TNF. IFNβ mainly induces interferon-stimulated genes by the Jan...
Autores principales: | Mariani, Mélissa K., Dasmeh, Pouria, Fortin, Audray, Caron, Elise, Kalamujic, Mario, Harrison, Alexander N., Hotea, Diana I., Kasumba, Dacquin M., Cervantes-Ortiz, Sandra L., Mukawera, Espérance, Serohijos, Adrian W. R., Grandvaux, Nathalie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721756/ https://www.ncbi.nlm.nih.gov/pubmed/31426476 http://dx.doi.org/10.3390/cells8080919 |
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