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Expression of the Major and Pro-Oncogenic H3K9 Lysine Methyltransferase SETDB1 in Non-Small Cell Lung Cancer

SETDB1 is a key histone lysine methyltransferase involved in gene silencing. The SETDB1 gene is amplified in human lung cancer, where the protein plays a driver role. Here, we investigated the clinical significance of SETDB1 expression in the two major forms of human non-small cell lung carcinoma (N...

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Detalles Bibliográficos
Autores principales: Cruz-Tapias, Paola, Zakharova, Vlada, Perez-Fernandez, Oscar M., Mantilla, William, Ramírez-Clavijo, Sandra, Ait-Si-Ali, Slimane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721806/
https://www.ncbi.nlm.nih.gov/pubmed/31398867
http://dx.doi.org/10.3390/cancers11081134