The Nucleolus: A Multiphase Condensate Balancing Ribosome Synthesis and Translational Capacity in Health, Aging and Ribosomopathies

The nucleolus is the largest membrane-less structure in the eukaryotic nucleus. It is involved in the biogenesis of ribosomes, essential macromolecular machines responsible for synthesizing all proteins required by the cell. The assembly of ribosomes is evolutionarily conserved and is the most energ...

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Detalles Bibliográficos
Autores principales: Correll, Carl C., Bartek, Jiri, Dundr, Miroslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721831/
https://www.ncbi.nlm.nih.gov/pubmed/31405125
http://dx.doi.org/10.3390/cells8080869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721831/
https://www.ncbi.nlm.nih.gov/pubmed/31405125
http://dx.doi.org/10.3390/cells8080869

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