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Src family kinase activity drives cytomegalovirus reactivation by recruiting MOZ histone acetyltransferase activity to the viral promoter

Human cytomegalovirus (HCMV) latency and reactivation rely on a complex interplay between cellular differentiation, cell signaling pathways, and viral gene functions. HCMV reactivation in dendritic cells (DCs) is triggered by IL-6 and extracellular signal-regulated kinase (ERK)–mitogen-activated pro...

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Detalles Bibliográficos
Autores principales: Dupont, Liane, Du, Lily, Poulter, Madeleine, Choi, Stephanie, McIntosh, Megan, Reeves, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721939/
https://www.ncbi.nlm.nih.gov/pubmed/31273084
http://dx.doi.org/10.1074/jbc.RA119.009667