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A junctophilin-caveolin interaction enables efficient coupling between ryanodine receptors and BK(Ca) channels in the Ca(2+) microdomain of vascular smooth muscle
Functional coupling between large-conductance Ca(2+)-activated K(+) (BK(Ca)) channels in the plasma membrane (PM) and ryanodine receptors (RyRs) in the sarcoplasmic reticulum (SR) is an essential mechanism for regulating mechanical force in most smooth muscle (SM) tissues. Spontaneous Ca(2+) release...
Autores principales: | Saeki, Takanori, Suzuki, Yoshiaki, Yamamura, Hisao, Takeshima, Hiroshi, Imaizumi, Yuji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721949/ https://www.ncbi.nlm.nih.gov/pubmed/31308177 http://dx.doi.org/10.1074/jbc.RA119.008342 |
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