Transcriptionally Active HERV-H Retrotransposons Demarcate Topologically Associating Domains in Human Pluripotent Stem Cells

Chromatin architecture has been implicated in cell-type-specific gene regulatory programs; yet, how chromatin remodels during development remains to be fully elucidated. Here, by interrogating chromatin reorganization during human pluripotent stem cell (PSC) differentiation, we discover a role for t...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yanxiao, Li, Ting, Preissl, Sebastian, Amaral, Maria Luisa, Grinstein, Jonathan, Farah, Elie N., Destici, Eugin, Qiu, Yunjiang, Hu, Rong, Lee, Ah Young, Chee, Sora, Ma, Kaiyue, Ye, Zhen, Zhu, Quan, Huang, Hui, Fang, Rongxin, Yu, Leqian, Belmonte, Juan Carlos Izpisua, Wu, Jun, Evans, Sylvia M., Chi, Neil C., Ren, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722002/
https://www.ncbi.nlm.nih.gov/pubmed/31427791
http://dx.doi.org/10.1038/s41588-019-0479-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722002/
https://www.ncbi.nlm.nih.gov/pubmed/31427791
http://dx.doi.org/10.1038/s41588-019-0479-7

Ejemplares similares