Prognostic factors associated with visual outcome of salvageable eyes with posttraumatic endophthalmitis

The purpose of this study is to evaluate the prognostic factors associated with visual outcomes in the salvageable eyes with posttraumatic endophthalmitis. We retrospectively reviewed the medical records of all patients diagnosed with posttraumatic endophthalmitis in our hospital between 2008 and 20...

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Autores principales: Lu, Xuehui, Xia, Honghe, Jin, Chuang, Chen, Weiqi, Siu-Chun Ng, Danny, Yan, Hua, Chen, Haoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722068/
https://www.ncbi.nlm.nih.gov/pubmed/31481709
http://dx.doi.org/10.1038/s41598-019-49117-w
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author Lu, Xuehui
Xia, Honghe
Jin, Chuang
Chen, Weiqi
Siu-Chun Ng, Danny
Yan, Hua
Chen, Haoyu
author_facet Lu, Xuehui
Xia, Honghe
Jin, Chuang
Chen, Weiqi
Siu-Chun Ng, Danny
Yan, Hua
Chen, Haoyu
author_sort Lu, Xuehui
collection PubMed
description The purpose of this study is to evaluate the prognostic factors associated with visual outcomes in the salvageable eyes with posttraumatic endophthalmitis. We retrospectively reviewed the medical records of all patients diagnosed with posttraumatic endophthalmitis in our hospital between 2008 and 2015. The following information was collected: age, sex, etiology, past medical history, clinical manifestations, wound location, microbiology, blood leukocyte counts, types of interventions, initial visual acuities and final visual acuities. Univariate and multivariate analyses were used to explore the factors associated with final best-corrected visual acuity. In total, 98 eyes of 98 patients were included in our study. Fifty-seven eyes underwent vitrectomy, 27 of them had silicone oil tamponade, 38 eyes received intravitreal ceftazidime only and 3 eyes received intracameral ceftazidime. In univariate analysis, poor initial visual acuity, presence of intraocular foreign body, number of intravitreal injections, retinal detachment and Zone 3 injury were associated with poor visual outcome. In multivariable analysis, poor initial visual acuity, presence of intraocular foreign body and number of intravitreal injections were independently associated with poor visual outcome. The silicone oil group had fewer repeated intravitreal injections than the group without oil tamponade. We concluded that the visual outcome of salvageable eyes with posttraumatic endophthalmitis is associated with initial visual acuity, presence of intraocular foreign body and number of intravitreal antibiotic injections.
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spelling pubmed-67220682019-09-17 Prognostic factors associated with visual outcome of salvageable eyes with posttraumatic endophthalmitis Lu, Xuehui Xia, Honghe Jin, Chuang Chen, Weiqi Siu-Chun Ng, Danny Yan, Hua Chen, Haoyu Sci Rep Article The purpose of this study is to evaluate the prognostic factors associated with visual outcomes in the salvageable eyes with posttraumatic endophthalmitis. We retrospectively reviewed the medical records of all patients diagnosed with posttraumatic endophthalmitis in our hospital between 2008 and 2015. The following information was collected: age, sex, etiology, past medical history, clinical manifestations, wound location, microbiology, blood leukocyte counts, types of interventions, initial visual acuities and final visual acuities. Univariate and multivariate analyses were used to explore the factors associated with final best-corrected visual acuity. In total, 98 eyes of 98 patients were included in our study. Fifty-seven eyes underwent vitrectomy, 27 of them had silicone oil tamponade, 38 eyes received intravitreal ceftazidime only and 3 eyes received intracameral ceftazidime. In univariate analysis, poor initial visual acuity, presence of intraocular foreign body, number of intravitreal injections, retinal detachment and Zone 3 injury were associated with poor visual outcome. In multivariable analysis, poor initial visual acuity, presence of intraocular foreign body and number of intravitreal injections were independently associated with poor visual outcome. The silicone oil group had fewer repeated intravitreal injections than the group without oil tamponade. We concluded that the visual outcome of salvageable eyes with posttraumatic endophthalmitis is associated with initial visual acuity, presence of intraocular foreign body and number of intravitreal antibiotic injections. Nature Publishing Group UK 2019-09-03 /pmc/articles/PMC6722068/ /pubmed/31481709 http://dx.doi.org/10.1038/s41598-019-49117-w Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Lu, Xuehui
Xia, Honghe
Jin, Chuang
Chen, Weiqi
Siu-Chun Ng, Danny
Yan, Hua
Chen, Haoyu
Prognostic factors associated with visual outcome of salvageable eyes with posttraumatic endophthalmitis
title Prognostic factors associated with visual outcome of salvageable eyes with posttraumatic endophthalmitis
title_full Prognostic factors associated with visual outcome of salvageable eyes with posttraumatic endophthalmitis
title_fullStr Prognostic factors associated with visual outcome of salvageable eyes with posttraumatic endophthalmitis
title_full_unstemmed Prognostic factors associated with visual outcome of salvageable eyes with posttraumatic endophthalmitis
title_short Prognostic factors associated with visual outcome of salvageable eyes with posttraumatic endophthalmitis
title_sort prognostic factors associated with visual outcome of salvageable eyes with posttraumatic endophthalmitis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722068/
https://www.ncbi.nlm.nih.gov/pubmed/31481709
http://dx.doi.org/10.1038/s41598-019-49117-w
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