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Milk-derived miRNA profiles elucidate molecular pathways that underlie breast dysfunction in women with common genetic variants in SLC30A2

Studies in humans and pre-clinical animal models show milk-derived miRNAs reflect mammary gland function during lactation. The zinc transporter SLC30A2/ZnT2 plays a critical role in mammary gland function; ZnT2-null mice have profound defects in mammary epithelial cell (MEC) polarity and secretion,...

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Detalles Bibliográficos
Autores principales: Kelleher, Shannon L., Gagnon, Annie, Rivera, Olivia C., Hicks, Steven D., Carney, Molly C., Alam, Samina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722070/
https://www.ncbi.nlm.nih.gov/pubmed/31481661
http://dx.doi.org/10.1038/s41598-019-48987-4