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Nb-induced stabilisation of p53 in HPV-infected cells

Cervical cancer is caused by a persistent infection of the mucosal epithelia with high-risk human papilloma viruses (HPVs). The viral oncoprotein E6 is responsible for the inactivation of the tumour suppressor p53 and thus plays a crucial role in HPV-induced tumorigenesis. The viral E6 protein forms...

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Detalles Bibliográficos
Autores principales: Steels, Anneleen, Vannevel, Laura, Zwaenepoel, Olivier, Gettemans, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722090/
https://www.ncbi.nlm.nih.gov/pubmed/31481667
http://dx.doi.org/10.1038/s41598-019-49061-9