Phosphorylation-dependent modulation of CFTR macromolecular signalling complex activity by cigarette smoke condensate in airway epithelia

Genetic and acquired loss-of-function defect of the cystic fibrosis transmembrane conductance regulator (CFTR) compromise airway surface liquid homeostasis and mucociliary clearance (MCC), culminating in recurrent lung inflammation/infection. While chronic cigarette smoke (CS), CS extract (CSE; wate...

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Detalles Bibliográficos
Autores principales: Schnúr, Andrea, Premchandar, Aiswarya, Bagdany, Miklos, Lukacs, Gergely L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722123/
https://www.ncbi.nlm.nih.gov/pubmed/31481727
http://dx.doi.org/10.1038/s41598-019-48971-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722123/
https://www.ncbi.nlm.nih.gov/pubmed/31481727
http://dx.doi.org/10.1038/s41598-019-48971-y

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