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Phosphorylation-dependent modulation of CFTR macromolecular signalling complex activity by cigarette smoke condensate in airway epithelia
Genetic and acquired loss-of-function defect of the cystic fibrosis transmembrane conductance regulator (CFTR) compromise airway surface liquid homeostasis and mucociliary clearance (MCC), culminating in recurrent lung inflammation/infection. While chronic cigarette smoke (CS), CS extract (CSE; wate...
Autores principales: | Schnúr, Andrea, Premchandar, Aiswarya, Bagdany, Miklos, Lukacs, Gergely L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722123/ https://www.ncbi.nlm.nih.gov/pubmed/31481727 http://dx.doi.org/10.1038/s41598-019-48971-y |
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