Multicomponent Conjugates of Anticancer Drugs and Monoclonal Antibody with PAMAM Dendrimers to Increase Efficacy of HER-2 Positive Breast Cancer Therapy

PURPOSE: Conjugation of nanocarriers with antibodies that bind to specific membrane receptors that are overexpressed in cancer cells enables targeted delivery. In the present study, we developed and synthesised two PAMAM dendrimer-trastuzumab conjugates that carried docetaxel or paclitaxel, specific...

Descripción completa

Detalles Bibliográficos
Autores principales: Marcinkowska, Monika, Stanczyk, Maciej, Janaszewska, Anna, Sobierajska, Ewelina, Chworos, Arkadiusz, Klajnert-Maculewicz, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722151/
https://www.ncbi.nlm.nih.gov/pubmed/31482205
http://dx.doi.org/10.1007/s11095-019-2683-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722151/
https://www.ncbi.nlm.nih.gov/pubmed/31482205
http://dx.doi.org/10.1007/s11095-019-2683-7

Ejemplares similares