Cargando…

Improving the Prediction of Local Drug Distribution Profiles in the Brain with a New 2D Mathematical Model

The development of drugs that target the brain is very challenging. A quantitative understanding is needed of the complex processes that govern the concentration–time profile of a drug (pharmacokinetics) within the brain. So far, there are no studies on predicting the drug concentration within the b...

Descripción completa

Detalles Bibliográficos
Autores principales: Vendel, E., Rottschäfer, V., de Lange, E. C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722198/
https://www.ncbi.nlm.nih.gov/pubmed/30091104
http://dx.doi.org/10.1007/s11538-018-0469-4