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Improving the Prediction of Local Drug Distribution Profiles in the Brain with a New 2D Mathematical Model
The development of drugs that target the brain is very challenging. A quantitative understanding is needed of the complex processes that govern the concentration–time profile of a drug (pharmacokinetics) within the brain. So far, there are no studies on predicting the drug concentration within the b...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722198/ https://www.ncbi.nlm.nih.gov/pubmed/30091104 http://dx.doi.org/10.1007/s11538-018-0469-4 |