Association Between Impaired Vα7.2+CD161++CD8+ (MAIT) and Vα7.2+CD161-CD8+ T-Cell Populations and Gut Dysbiosis in Chronically HIV- and/or HCV-Infected Patients

Both HIV and HCV infections feature increased microbial translocation (MT) and gut dysbiosis that affect immune homeostasis and disease outcome. Given their commitment to antimicrobial mucosal immunity, we investigated mucosal-associated invariant T (MAIT) cells and Vα7.2+CD161- T-cell frequency/fun...

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Detalles Bibliográficos
Autores principales: Merlini, Esther, Cerrone, Maddalena, van Wilgenburg, Bonnie, Swadling, Leo, Cannizzo, E. Stefania, d’Arminio Monforte, Antonella, Klenerman, Paul, Marchetti, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722213/
https://www.ncbi.nlm.nih.gov/pubmed/31555223
http://dx.doi.org/10.3389/fmicb.2019.01972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722213/
https://www.ncbi.nlm.nih.gov/pubmed/31555223
http://dx.doi.org/10.3389/fmicb.2019.01972

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